Wisconsin Alumni Research Foundation

Animals, Agriculture & Food
Animals Agriculture Food
Yeast Strains With Selected Or Altered Mitotypes And Methods Of Making And Using The Same
WARF: P180359US02

Inventors: Christopher Hittinger, David Peris Navarro, EmilyClare Baker


The Invention
Herein we demonstrate that the mitochondrial genome influences temperature tolerance in Saccharomyces yeasts. The present invention provides methods for manipulating the mitotype of yeast, including methods to produce synthetic yeast hybrids with a selected mitotype and methods to exchange the native mitochondrial DNA (mtDNA) present in polyploid yeast with mtDNA from a desired source. Saccharomyces cerevisiae x Saccharomyces eubayanus hybrids with selected mitotypes are also provided. The yeast and methods of the present invention may be utilized in a variety of applications, including in fermentation to produce beer and wine.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854

WARF