Staff at the Wisconsin State Laboratory of Hygiene have prepared influenza virus isolate A/Wisconsin/588/2019 (FR-1758), as part of their influenza surveillance work through the national CDC-led influ...
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Detection of genetic aberrations using nucleic acids as biomarkers can be a powerful strategy for disease diagnosis and progression monitoring; however, the high heterogeneity of cells within a patien...
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UW-Madison researchers have identified and validated a set of human T cell specific biomarkers that can predicti graft-vs-host disease (GVHD) and/or relapse following allogeneic hematopoietic stem cel...
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The UW researcher identified IgG sequences that bind Rheumatoid Factors (RFs) involved in rheumatoid arthritis (RA) and/or COVID-19. These peptides could be used as diagnostic reagents to monitor the ...
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UW-Madison researchers have developed mass spectrometry (MS) compatible nanoparticles for the selective capture and enrichment of low abundance proteins. The surface of superparamagnetic nanoparticles...
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Using two sets of comparative patient samples (hospitalized COVID-19 patients vs controls from 3 years ago, and hospitalized COVID-19 patients vs patients hospitalized for other conditions), the inven...
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Sjögren’s syndrome is one of the most common systemic rheumatic diseases, affecting an estimated 4 million Americans. In roughly half of patients, this disorder occurs in the presence of another au...
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UW-Madison researchers have developed three novel monoclonal antibodies that all have exceptional activity against human and mouse GATA2.   
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UW – Madison researchers have determined that SARS-CoV-2 infection induces antibodies against both structural and non-structural proteins and they identified epitopes in the SARS-CoV-2 membrane ...
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The current gold standard method for COVID-19 testing is a multi-step protocol 25 involving RNA extraction using column-based or magnetic bead-based methods, followed by RT-qPCR-based detection of the...
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Prostate cancer is the most commonly diagnosed disease in men. Current clinical practice for prostate cancer screening uses the prostate specific antigen (PSA) test. However, PSA-based screening detec...
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Systems for monitoring metabolites may include a sample collection system and a urinalysis system of or for a toilet.  The sample collection system may be automated to collect sample urine from a...
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Differentially methylated positions associated with hypersomnolence, idiopathic hypersomnia, and long sleep time are provided herein along with biomarker panels thereof and methods of diagnosing and p...
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The present disclosure provides for methods of diagnosing and treating bacterial infections. Human Intelectin 1 (hIntL-1) has been shown to bind selectively to glycan components on bacteria including ...
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A method of detecting the presence of a prostate cancer field defect in a human subject comprising the step of (a) obtaining genomic DNA from the human subject and (b) quantitating methylation in at l...
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A method of detecting the presence of a prostate cancer in a human subject comprising the steps of (a) obtaining a histologically normal prostate tissue sample from the patient and (b) quantifying the...
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The present invention relates to antigen-specific immune regulatory response. Methods for detecting an antigen-specific immune regulatory response, methods for selecting candidate vaccine recipients, ...
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Devices and methods for using changes in the configuration of micrometer sized dispersed liquid crystal domains to detect or quantify analytes in a test sample, including endotoxin lipopolysaccharide ...
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The disclosure relates to laboratory and bioinformatics methods for isolating, detecting, and characterizing microbes in biological samples using metagenomic approaches.
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Described herein is cancer biomarker, e.g., a vesicle, capture surface that includes a substrate, a first plurality of nanoparticles attached to the substrate; a plurality of bifunctional tethers, whe...
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The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use.
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Mycobacterial-specific biomarkers and methods of using such biomarkers for diagnosis of mycobacterial infection in a mammal are disclosed.
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It is estimated that half of new HIV infections in the U.S. are from patients who know they are HIV-positive but underestimate their transmissibility. Identifying and monitoring the latent HIV reservo...
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Colorectal cancer is a major cause of cancer-related morbidity and mortality in developed nations, causing more than 600,000 deaths worldwide every year. While early detection of localized colorectal ...
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Advances in screening and detection have led to an increase in the diagnosis of early stage breast cancer. Plotting the optimal course of treatment (i.e., more or less aggressive) remains a challenge,...
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