SYSTEM AND METHOD FOR MONITORING LESION PROGRESSION OVER MULTIPLE MEDICAL SCANS
Inventors: Robert Jeraj, Victor Fernandes
Metastasis is the leading cause of cancer-related mortality. In metastasis, cells of a primary cancer break away from where they were first formed and travel through the body to create new lesions. Each metastatic lesion may respond differently to treatment and, accordingly, lesion-level assessment may be necessary for a complete understanding of disease response. Such lesion-level assessment, however, is difficult as it requires manual matching of as many as hundreds of corresponding lesions, which is a tedious, subjective, and error-prone task, and is therefore rarely performed in practice.
UW-Madison researchers have developed a method for assessing disease progression and treatment as revealed by multiple lesions between time-separated scans of a patient through a global process which assesses overlap between all pairs in the scan sequence and links lesions in different images to maximize overlap globally. The system is implemented in software linking lesions among different medical scans taken over time to better reveal disease progression.
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