Drug Delivery
Lipid Nanoparticles Formed by Lipidoids for Efficient Delivery of Nucleotide Drugs and Biologics
WARF: P230451US02
Inventors: Shaoqin Gong, Ruosen Xie
The Invention
UW-Madison researchers have developed a lipid-oligomer nanoparticle (lipomer) for packaging and delivery of mRNA in vivo. The lipomer displays high delivery efficiency, versatile surface chemistry for ligand conjugation, high payload loading content (≥10 wt%), relatively small particle sizes (~80 nm), good biodegradability and biocompatibility, and ease of manufacturing, transport, and storage.
Additional Information
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Tech Fields
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