Wisconsin Alumni Research Foundation

New Strategies to Drug Challenging Targets by Exploiting Covalent Targeting, Beyond Rule of 5 Bitopic Ligands and Binary Pharmacology


The GTP-ase K-Ras represents the most frequently altered oncogene in cancer patients. Directly targeting K-Ras is difficult due to its picomolar affinity for GTP/GDP and the absence of easily identifiable allosteric sites. Kevan M. Shokat, a professor of cellular and molecular pharmacology at UCSF, a professor of chemistry at UC Berkeley and an investigator with…

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Discovery Outreach at Juneteenth Celebration in the Park

Penn Park 2101 Fisher St., Madison

Our Discovery Outreach team will be part of Kujichagulia‘s Juneteenth celebration of Black history and the emancipation of slavery. Join us outside at Penn Park! Make your own self-watering planter using recyclable containers, investigate the colors of the rainbow using candy and water, explore bacteria in the soil with Tiny Earth, get ready for the…

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Red Cross Blood Drive

First Unitarian Society 900 University Bay Drive, Madison

Every day, blood donors help patients of all ages: accident and burn victims, heart surgery and organ transplant patients, and those battling cancer. In fact, every two seconds, someone in the U.S. needs blood. Join us for our annual summer blood drive! This year, we’re moving the drive, which usually takes place at the Discovery…

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