The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge w...
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A “localizable” systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape o...
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A syringe adapter having a syringe holder and an actuator are disclosed. The syringe holder may include a fixed portion that may receive a barrel of a syringe and an adjustable portion adjustably posi...
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A system and method are provided for a guide system for guiding an interventional medical instrument toward a region of interest (ROI) along a predetermined trajectory path. The guide system comprises...
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A piezoelectric artificial artery can be 3D printed to provide the real-time precise sensing of blood pressure and vessel motion patterns enabling early detection of partial occlusions. An electric-fi...
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The present invention provides a vaginal pessary that offers mid-urethral support and is anchored proximate the cervix by a proximal annulus engaging opposing walls of the vagina and supporting a dist...
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A method and apparatus of early-stage detection of glaucoma and other optic nerve or retinal diseases employs dynamic images that are processed differently by Y-like cells and Xlike cells to provide a...
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An interface unit for epicardial pacemaking and telemetry monitoring connects a pacemaker and bedside monitor for simultaneous pacing during electrogram visualization using epicardial pacing leads. Th...
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Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonuclei...
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A disposable speculum for an otoscope provides an attached forward-facing pressure sensitive adhesive for adhering to and extracting foreign bodies from the ear canal. Attaching the pressure sensitiv...
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The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
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Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral l...
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Disclosed are formulations for providing an active agent. Formulations include a carrier including an active agent and mineral coated microparticles wherein an active agent is adsorbed to the mineral....
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A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The elect...
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Disclosed herein are methods for modifying a substrate having a hydrophobic surface. Also disclosed are modified hydrophobic substrates. The modified hydrophobic substrates and methods disclosed herei...
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Disclosed herein are novel wavy, multi-component vascular grafts (WMVGs) with a wavy inner layer of rigid biopolymer fibers and an outer layer of elastic biopolymer fibers and a method for preparing W...
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A disposable speculum for an otoscope provides a sheath adapted to cover an elongate otoscope probe and providing inwardly extending tabs that are adapted to flex outward when the speculum is inserted...
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Aspects of the disclosure are directed to methods and/or apparatuses involving the deployment and coupling of catheters. As may be implemented in accordance with one or more embodiments, each of first...
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The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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A comfortable device for treating sleep apnea incorporates a mask, a flexible hose and a chamber for collecting expired air containing CO2. A sensor detects apnea and a control system automatically ad...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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A method and device are provided for detecting a target in a biological sample. The target binds to a solid phase substrate. First and second cavities in a plate are filled with an oil. The first and ...
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The importance of face shields in preventing the transmission of infectious agents is increasingly well established. Typically, a face shield will include a headband that can be clamped about the head...
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In 2016, approximately 135,000 new cases of colon and rectal cancers will be diagnosed and nearly 50,000 will die from this disease, making it the one of the most common causes of cancer related death...
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