Aspects of the disclosure are directed to methods and/or apparatuses involving the deployment and coupling of catheters. As may be implemented in accordance with one or more embodiments, each of first...
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The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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A comfortable device for treating sleep apnea incorporates a mask, a flexible hose and a chamber for collecting expired air containing CO2. A sensor detects apnea and a control system automatically ad...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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A method and device are provided for detecting a target in a biological sample. The target binds to a solid phase substrate. First and second cavities in a plate are filled with an oil. The first and ...
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In 2016, approximately 135,000 new cases of colon and rectal cancers will be diagnosed and nearly 50,000 will die from this disease, making it the one of the most common causes of cancer related death...
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A new cancer treatment being studied at a few major centers including UW Health is CAR T (Chimeric Antigen Receptor T cell) therapy. CAR T therapy uses a patient's own cells and 'reengineers&#...
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The importance of T cells in immunotherapy is driving the development of technologies to better characterize T cells and improve therapeutic efficacy. One specific objective is assessing antigen-induc...
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The separation or isolation of proteins from a heterogeneous mixture is a common practice in scientific experimentation and the manufacturing of biologic reagents. Commercially available kits and cur...
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Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Slippery liquid-infused porous surfaces (SLIPS) are an emerging class of materials with unique antifouling properties and applications ranging from biomedical device coatings and consumer products to ...
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Bacterial contamination is a major risk in biologics manufacturing and the presence of endotoxin, an outer membrane component of Gram-negative bacteria, is vigorously tested for in protein and DNA/RNA...
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Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bone and joint diseases account for half of all chronic conditions in adults over the age of 50. Current c...
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Noise level in the workplace is a concern and is monitored by the Occupational Safety and Health Administration (OSHA). In many instances, providing some form of hearing protection is an easy solution...
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Selection intensity for higher milk production in dairy cattle has contributed to a decline in fertility, posing a challenge to dairy producers. Despite technological advances, the pregnancy rate of c...
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Growth factor regulation is a key function of the extracellular matrix and critical for proper blood vessel growth and maturation during wound healing. In particular, blood vessel sprouting is essenti...
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Collagen is the most abundant protein in vertebrates, providing support to virtually every tissue including skin, bone and blood vessel. It is of critical importance in wound healing.Given its signifi...
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Cancer treatment planning remains an ongoing challenge to oncologists and patients alike, with each cancer being genetically unique and requiring personalized approaches. Greater outcome success will ...
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Each year approximately 780,000 Americans experience a new or recurrent stroke.  Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of long...
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UW-Madison researchers previously described a method of determining whether or not an animal is suffering from a catabolic change by sampling isotope changes in breath or blood.
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The catabolic state refers to the condition where the body uses stores of carbohydrates, amino acids or fats as a source of energy for maintenance. The catabolic state may be induced by infection, dis...
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An otoscope is a classic, handheld medical device that allows a doctor to look into the ear canal and tympanic membrane (eardrum). This is important for diagnosing ear infections, membrane ruptures an...
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An estimated eight out of 10 people will be affected by a spine condition during their lifetime, making treatment options like spinal fusion surgery imperative. Spinal fusion is a surgical procedure i...
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Walking impairment can be caused by many factors such as aging, traumatic brain injury, cerebral palsy and other conditions that disrupt balance and posture. Stroke, for example, is the leading cause...
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