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180 Results for 'Medical Devices'
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Technology
Electromechanical Force-Magnitude, Force-Angle Sensor
UW-Madison researchers previously described a piece of exercise equipment for rehabilitation of stroke patients and sport-specific training of athletes that allows users to measure and train the magni...
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Kreg Gruben, Matthew Schmidt | P06028US
Technology
Medical Shunt and Valve for Regulating Bodily Fluids, Especially Cerebral Spinal Fluid
No way currently exists to prevent or cure hydrocephalus, which is the abnormal accumulation of cerebral spinal fluid (CSF) in the brain. The most effective treatment involves surgical insertion of a ...
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Christopher Luzzio, Joshua Medow | P03355US
Technology
Optimizing Probes to Improve Spectroscopic Measurement in Turbid Media
Fiber optic probes can be used for spectroscopic measurement of tissue. A fiber optic tube emits light on one side of the tissue that is absorbed and measured on the other side by fiber optic detector...
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Gregory Palmer, Nirmala Ramanujam | P06032US
Technology
Bioactive and Biocompatible Copolymers for Use in Medical Implants
Many human diseases and conditions can be treated by implanting devices within the body. However, these devices may be rejected by the body’s immune system or “fouled” by the accumulation of bac...
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Kristyn Masters, Wendy Crone, Fangmin Xu | P07185US
Technology
Novel Assay for Measuring Stress-Induced CREB Phosphorylation
CREB is a transcription factor that has been implicated as a critical regulator of neuronal function and survival. Knockout mice lacking CREB exhibit a disease similar to ataxia telangiectasia, a neur...
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Randal Tibbetts, Yuling Shi | P04048US
Technology
Integrated, Miniaturized Fiber Optic Probe for Light-Based Diagnostics
Light-based diagnostics are used to create images of human tissue to detect the development of diseases like cancer. The popularity of light-based diagnostics is growing due to their non-intrusive nat...
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Thomas Kuech, Nirmala Ramanujam, Leon McCaughan | P09149US
Technology
Bioactive Device for Improved Vascular Aneurysm Occlusion and Healing
As many as one in 20 people in the United States are estimated to have some form of cerebral aneurysm. The majority of cerebral aneurysms are treated from inside the blood vessel, which is referred to...
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Kristyn Masters, Wendy Crone, Roham Moftakhar, Fangmin Xu | P07117US
Technology
Electrode Array for Radiofrequency Tissue Ablation
The liver is a common site for both primary and metastasizing cancer. Surgical resection, the preferred treatment for liver cancer, is a time consuming procedure during which the surgeon must cut thro...
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Dieter Haemmerich, David Mahvi, John Webster, David Schutt | P03367US
Technology
Fan-Beam Microwave Horn for Improved Organ Resection
Liver cancer is the fifth most common cancer in the world and is frequently fatal. Surgical resection currently is the preferred treatment for liver cancer. During the time-consuming treatment, a ...
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David Mahvi, Mark Converse, Punit Prakash, John Webster | P07328US
Technology
Biomaterial Scaffolds for the Repair and Regeneration of Intervertebral Discs and Articulating Joints
Biomaterial scaffolds for tissue engineering perform three primary functions. They provide temporary support, provide a connected porosity to enhance tissue regeneration and guide the regenerated ti...
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William Murphy, Chia-Ying Lin, Frank LaMarca, Stephn Feinberg, James Adox, Scott Hollister | P08447US
Technology
Computational Algorithms for Identifying, Suppressing and Reversing Epilepsy
Epileptogenesis, or the occurrence of spontaneous seizures, is considered to be a learned response due to brain plasticity. The development of the condition requires circuits in the brain to possess...
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David Hsu, Murielle Hsu, John Beggs | P08298US
Technology
Biologically Active Sutures Enhance Tissue Healing Following Surgical Procedures
Musculoskeletal conditions cost an estimated $254 billion each year in the United States, and bone and joint diseases account for half of all chronic conditions in adults over the age of 50. Bone-te...
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William Murphy, Jae Sung Lee, Mark Markel, Ben Graf, Geoffrey Baer, Yan Lu | P09201US
Technology
Phospholipase Activity Provides a Simple Test for Systemic Inflammation in Acute and Chronic Disease
The inflammatory response plays a role in illnesses from injury to infections to allergies. Initiation of inflammation involves the activation of immune cells that trigger a cascade of events leadin...
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Keith Meyer, Francis Tsao | P02007US
Technology
Method for Extraction of Optical Properties from Diffuse Reflectance Spectra
Diffuse reflectance spectroscopy can be used to measure tissue absorption and scattering, which reflect the intrinsic physiological and structural properties of tissue respectively. This technique can...
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Nirmala Ramanujam, Gregory Palmer | P05045US
Technology
Methods for Identifying Neuronal Spikes
Electrodes placed deep within the brain can deliver electrical impulses directly to nerve centers for the treatment of movement disorders such as Parkinson’s disease and dystonia. The electrodes mus...
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Erwin Montgomery, He Huang, John Gale | P05217US
Technology
Localized Delivery of Nucleic Acid by Polyelectrolyte Assemblies
Thin films and coatings that allow the sustained release of DNA from surfaces play an important role in the development of localized approaches to gene therapy. For example, polymer-coated intravascul...
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David Lynn, Jingtao Zhang, Christopher Jewell, Nathaniel Fredin | P05195US
Technology
Improved Method of Fluorescence Spectroscopy using Monte Carlo Simulation for Medical Diagnostics
The early detection of disease or malignancy can greatly increase the probability of full recovery, especially in the case of cancers. Optical diagnostic techniques, such as diffuse reflectance and ...
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Nirmala Ramanujam, Gregory Palmer | P06332US
Technology
Oral-Lever Resistance Exercise Device
The tongue loses strength as a result of aging, illness or injury, often resulting in loss of swallowing capacity (dysphagia) that in turn may lead to malnutrition, dehydration or pneumonia. NIH-funde...
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JoAnne Robbins, Jacqueline Hind, Angela Hewitt | P05037US
Technology
Neural Probe Array for Stable, Reliable Long-Term Implant Function
Electrodes inserted into the brain can be used to monitor and record neural activity. However, conventional electrode arrays have several limitations, including a short functional life.
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Justin Williams, P. Charles Garell | P04202US
Technology
A Flow Control Device for the Treatment of Intracranial Aneurysms
Cerebral aneurysms develop when the wall of a cerebral artery becomes weakened and the blood vessel balloons. Intracranial aneurysms are estimated to affect between three and six percent of the adult ...
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Charles Strother, Jingfeng Jiang | P07486US
Technology
Improved Brain-Computer Interface Technology for Long-Term Cortical Stimulation or Recording
Brain-computer interface (BCI) technology has the potential to create new treatments for severe motor impairment. Devices to acquire signals from the brain are essential components of BCI systems. ...
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Justin Williams, Karl Sillay, Jiwan Kim, David Niemann, Azam Ahmed | P08317US
Technology
Improved Wound Healing Using Patterned Gradients of Immobilized Biomolecules
More than five million people in the United States are afflicted with chronic skin wounds, resulting in billions of dollars in medical expenses each year. The incidence of chronic wounds is expected t...
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Kristyn Masters, Tracy Jane Stefonek | P07291US
Technology
New Method That Allows Unsupervised Cluster Analysis
Just as two points may appear closer in two-dimensional space than they actually are in three dimensions, it is difficult to tell under multiple dimensions how similar two points are. To sort data wit...
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Erwin Montgomery, Amir Assadi, He Huang | P04257US
Technology
Depth-Resolved Reflectance Instrument
Phsyicians often use microscopic visual inspection followed by biopsy to detect cancer; however, this method is limited in many ways. Optical techniques are a promising alternative that allows clinici...
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Nirmala Ramanujam, Liu Quan | P05015US
Technology
Injection Molding of Biodegradable Tissue Engineering Scaffolds
Biodegradable scaffolds with highly interconnected pores are potentially useful in tissue engineering. A rigid, highly porous platform could be used to guide growth in tissues such as bone, cartilage ...
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Lih-Sheng Turng, Adam Kramschuster | P07200US