Wisconsin Alumni Research Foundation

Technology

RSV Virus-Like Particles And Methods Of Use Thereof

The present disclosure relates to vims-like particles and vaccine compositions for inducing immunity and preventing respiratory syncytial vims (RSV) infection. Specifically, the disclosure provides vi...
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Elizabeth Wright, Larry Anderson, Binh Ha | P200021US02

Technology

2-methylene-19-nor Vitamin D2 Compounds

2-Methylene-19-nor-24(S) and 24(R) derivatives of 1α,25-dihydroxyvitamin D2 are disclosed. These compounds are characterized by minimal bone calcium mobilization activity and relatively high intestin...
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Hector DeLuca, Sumithra Gowlugari, Rafal Sicinski | P02026US

Technology

Drugs To Prevent Hpv Infection

A method of inhibiting HPV virus infection is disclosed. In one embodiment, the method involves exposing a papillomavirus to an effective amount of a compound selected from the group consisting of Com...
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Paul Lambert, Paul Ahlquist, Dohun Pyeon, Hao-Shun Huang | P08406US02

Technology

19-nor-vitamin D Analogs With 1,2-dihydrofuran Ring

19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 1α-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds ex...
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Hector DeLuca, Katarzyna Sokolowska, Rafal Sicinski, Lori Plum, Margaret Clagett-Dame, Agnieszka Glebocka | P08399US

Technology

Methods For Preventing And Attenuating Hyperphosphatemia

It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at ris...
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Mark Cook, Keith Crawford, Erica Hellestad, Martin Petkovich, Christian Helvig | P06481US

Technology

Metabolic-based Methods For Modulating Gene Expression

This invention provides methods for modulating cellular gene expression for genes operably linked to an NRSE element that is recognized by an NRSF transcriptional repressor, by changing the concentrat...
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Thomas Sutula, Avtar Roopra, Barry Schoenike | P05137US

Technology

Influenza Virus Replication For Vaccine Development

The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isola...
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Yoshihiro Kawaoka, Gabriele Neumann, Jihui Ping | P150360US02

WARF