Wisconsin Alumni Research Foundation

Technology

Streamlined Design for Transferring Analytes

Polymerase chain reaction (PCR) is used to generate copies of a particular DNA sequence. The technique is common and indispensable in many research applications. Unfortunately, methods for isolating/p...
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David Beebe, Ben Casavant, David Guckenberger, Scott Berry | P130361US01

Technology

Circulating Tumor Cell Assay Using Simple Blood Draw

Circulating tumor cells (CTCs) are cells shed from tumor deposits that flow into the bloodstream. They are detected at a frequency of about one CTC per one billion surrounding blood cells. The great h...
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David Beebe, Joshua Lang, Ben Casavant, Scott Berry, Lindsay Strotman | P130171US01

Technology

Microwell Moat Prevents Spillover

The ability to study single cells has become indispensable, helping researchers identify characteristics and behaviors otherwise hidden using population averages. By obtaining multiple measures per ce...
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Jay Warrick, John Yin, Stephen Lindsay | P120353US01

Technology

Device Uses Air Gap for Easier Fraction Isolation

Isolating analytes from complex biological samples is one of the most crucial steps in many areas of biological research and clinical diagnostics. Paramagnetic particles (PMPs) or beads are important ...
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David Beebe, Scott Berry | P130107US01

Technology

Microfluidic Device for Drug Delivery

Oral ingestion of pharmaceuticals is considered the safest, most convenient and most economical method of administering drugs. However, many pharmaceuticals cannot be delivered orally because they are...
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David Beebe, Michael MacDonald, David Eddington, Glennys Mensing | P04240US

Technology

Autonomous Self-Regulating Microfluidic System

Currently, no simple methods for the economical construction of complex microsystems exist. Some feedback systems have been constructed, but their complicated fabrication hinders their application.
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David Beebe, Jeffrey Moore, Robin Liu, David Eddington | P01314US

Technology

Method and Structure for Microfluidic Flow Guiding

Microfluidic devices are miniature systems that pump, mix, monitor and control small quantities of liquids. These systems have a number of applications, including painless drug delivery and analysis o...
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David Beebe, Jeffrey Moore, Bin Zhao | P01118US

Technology

Variable-Focus Lens Assembly

One component of lab-on-a-chip technology is on-chip microlenses for optical analysis. Prior investigators have demonstrated tiny optical lenses with variable focal lengths. These lenses use specializ...
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Hongrui Jiang, Abhishek Agarwal, Liang Dong, David Beebe | P05131US

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