UW-Madison researchers have developed a method for differentiation of human pluripotent stem cells (hPSCs) into endothelial cells (ECs) resulting in a model having improved fidelity to BBB gene expres...
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UW-Madison researchers previously discovered that Escherichia coli BL21(DE3) and commercially available derivatives of it carry a deletion that results in an in-frame fusion of sufA and sufB genes wit...
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UW-Madison researchers previously discovered that Escherichia coli BL21(DE3) and commercially available derivatives of it carry a deletion that results in an in-frame fusion of sufA and sufB genes wit...
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UW-Madison researchers previously discovered that Escherichia coli BL21(DE3) and commercially available derivatives of it carry a deletion that results in an in-frame fusion of sufA and sufB genes wit...
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UW-Madison researchers have developed an immortalized keratinocyte cell line from the little brown bat (a species that is now endangered). They utilized that cell line to create a model of bat hiberna...
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A UW-Madison researcher has developed a novel cell line for studying the dynamics of the protein Ist1. They added a HaloTag onto the 3’ end of IST1 in a human RPE1 cell line. This cell lines provide...
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UW-Madison researchers have developed a petri dish with locking mechanisms for single-handed operations. As cell culture workflows can be sensitive to contamination, single-handed operation allows use...
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UW-Madison researchers have developed a new screening approach for identifying host factors that impact influenza viral production after the initial infection, and have used the screen to identify doz...
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A UW-Madison researcher has created a cell line capable of growing LDV virus in vitro. The inventor explains that he made an educated guess as to what the receptor for this virus might (CD163) be and ...
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A UW-Madison researcher has developed FcRn-overexpressing cell lines that are susceptible to arterivirus infection. Through a genetic screen, the inventor discovered that the neonatal Fc receptor (FcR...
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A UW-Madison researcher has established a cell line, called VACO6, from a discarded tissue specimen of a surgically resected primary human colon cancer. The detailed characteristics of the clinical do...
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UW-Madison researchers have developed a number of variants of lytic strain L. reuteri ∆Φ1attB1∆Φ2∆attB2 (WARF case P170020). They are: L. reuteri∆Φ1, in which prophage #1 is deleted from th...
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A UW-Madison researcher has developed a Rhesus Macaque induced pluripotent stem cell (iPSC) line, called the Rh2431 iPSC line. 
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A UW-Madison researcher has developed a Cynomolgus Macaque induced pluripotent stem cell (iPSC) line, called the cy0657 iPSC line.
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UW-Madison researchers disclose a new method for differentiating brain mural cells – encompassing pericytes and vascular smooth muscle cells – from hPSCs. The inventors used their previously discl...
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Normal vibration of vocal folds (aka vocal cords) depends on the tissue's composition and viscoelasticity. When that composition is altered by scarring or damage, the vibratory functionality of th...
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The commercially available E. coli strain BL21 λDE3 is commonly used for inducibly overexpressing recombinant proteins. Many derivatives of BL21 cells have been developed and commercialized, with pro...
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UW Madison researchers' present invention is a set of two, new transgenic mouse multiple myeloma (MM) cell lines. Transgenic mice were developed expressing mutations in RAS pathway genes found in ...
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UW-Madison researchers have developed two cell lines derived from RPE-1 cells (which were obtained from ATCC), an immortalized, non-transformed human epithelial cell line. “PLK4 WTflox/Delta” is a...
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Basal cell carcinoma (BCC) is the most common type of skin cancer, with around 3 million cases diagnosed each year. BCC involves the basal cells, which are in the deepest layer of the epidermis, the o...
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HERG-1 (human ether-a-go-go-related gene) potassium channels mediate repolarization of cardiac action potentials. Loss of function mutations in hERG-1 can result in long QT syndrome, an inherited diso...
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GATA-binding-factor 2 (GATA2) is a transcription factor involved in stem cell maintenance and hematopoietic development. The gene encoding GATA2 often suffers germline and somatic mutations, which res...
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Fragile X syndrome (FXS) is a genetic disorder characterized by mild to moderate intellectual disability and a characteristic phenotype. It is the most common form of inherited intellectual disability...
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Down syndrome (Trisomy 21, Ts21) is a condition caused by having an extra copy of the 21st chromosome due to an error in cell division. People born with Down syndrome have a characteristic phenotype a...
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Mitochondrial function plays a central role in longevity and healthy aging, and delayed aging by calorie restriction activates PGC-1a (peroxisome proliferator-activated receptor gamma coactivator-1 al...
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