UW-Madison researchers have developed a blood-brain barrier (BBB) model with in vivo-like BBB transcytosis properties using a new method that improves the fidelity of highly selective, cross-barrier ...
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UW-Madison inventors have developed a new PACE-based platform for rapid discovery of bioactive cyclic peptide protein aggregation inhibitors. By linking cyclic peptide activity to phage reproduction, ...
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The present invention from UW-Madison and USDA Forest Service Forest Products Lab (FPL) researchers is an automated system for identifying the source of wood in a charcoal product. The inventors emplo...
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UW-Madison researchers have developed a method to optimize the production of reuterin in bacterial cells that contain the reuterin production pathway (i.e., the pdu operon). The inventors compared the...
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A UW-Madison researcher has developed a novel cell line for studying the dynamics of the protein Ist1. They added a HaloTag onto the 3’ end of IST1 in a human RPE1 cell line. This cell lines provide...
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UW-Madison researchers have developed a set of vectors for expressing nanobodies. The researchers engineered a vector system for transferring nanobodies between bacterial and mammalian expression syst...
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UW-Madison researchers have developed a petri dish with locking mechanisms for single-handed operations. As cell culture workflows can be sensitive to contamination, single-handed operation allows use...
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UW-Madison researchers have developed methods for identifying nucleic acid sequence information using single molecule measurements that provide simple, information-rich workflows with high sensitivity...
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UW-Madison researchers have developed ferritin-targeting proteolysis targeting chimeras (PROTACs) to establish an iron excess stress inside cancer cells. The PROTAC structure contains oleic acid for b...
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UW-Madison researchers have developed an RNA barcode method to measure transcripts produced under an inducible promoter without the need for deep sequencing. The method involves adding a random RNA ba...
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UW-Madison researchers have developed HeLa cell-adapted Rhinovirus-C (RV-C) variants that induce a strong cytopathic effect and replicate vigorously in HeLa-E8 cells. The inventors had previously show...
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UW-Madison researchers have developed a reporter cell line for identifying compounds that promote endothelial cell differentiation and nitric oxide production and identified four compounds that promot...
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UW-Madison researchers have developed a new combination adjuvant composition (dubbed QTAP) that combines two safe adjuvants (Quil-A and DOTAP) using a nanoparticle preparation protocol developed by th...
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UW-Madison researchers have developed a washed platelet extract with increased platelet growth factor concentration and decreased total protein relative to platelet rich plasma, and methods of making ...
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UW-Madison researchers have developed a new screening approach for identifying host factors that impact influenza viral production after the initial infection, and have used the screen to identify doz...
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Two UW-Madison researchers have developed a programmable reaction-diffusion system, derived from two small bacterial proteins MinD and MinE, that can be encoded into mammalian cells. In addition, the ...
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Research into new therapies for skin diseases is challenging for a number of reasons. As is known, skin cells are exposed to both atmospheric air and liquids within the body. However, conventional cel...
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Metagenomics is the study of genetic material from environmental samples for detecting microbes, especially pathogens. It is increasingly used within clinical and industrial settings. While metagenomi...
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UW-Madison inventors have developed a device that controls a series of actuators mounted onto various inverted microscopes (i.e. Nikon TiE II) to add 3D bioprinting and pick and place capabilities. Th...
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UW-Madison researchers have developed a set of novel isobaric chemical tags, DiLeu-Biotin-Azide (DBA), that could be useful in proteomics, particularly quantification of post translational modificatio...
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A UW-Madison researcher has created a cell line capable of growing LDV virus in vitro. The inventor explains that he made an educated guess as to what the receptor for this virus might (CD163) be and ...
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A UW-Madison researcher has developed FcRn-overexpressing cell lines that are susceptible to arterivirus infection. Through a genetic screen, the inventor discovered that the neonatal Fc receptor (FcR...
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UW-Madison researchers have developed and validated a novel “parasitome” method to accurately characterize parasites in samples. Like published metabarcoding protocols, the new method consists of ...
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Su-Chun Zhang, a world-renowned neuroscientist and pioneer in stem cell research, has developed a method for printing neural tissues that allows cells to form neural networks in vitro. The human brain...
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UW-Madison researchers have identified several tryptophan decarboxylase (TDC) mutations for improving enzymatic activity towards substituted tryptamines. Having identified these mutations, the researc...
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