A UW-Madison researcher has developed a Cynomolgus Macaque induced pluripotent stem cell (iPSC) line, called the cy0657 iPSC line.
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UW-Madison researchers disclose a new method for differentiating brain mural cells – encompassing pericytes and vascular smooth muscle cells – from hPSCs. The inventors used their previous...
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The present invention is a novel, primatized mouse model for studying the immune system of nonhuman primates in a relatively low-cost mouse. The UW-Madison inventor used a different source of immune c...
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UW researchers have developed modified genetically encoded plasma membrane voltage probes for monitoring mitochondrial and ER membrane voltage gradients. A fluorescence protein tag was coupled with a ...
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UW-Madison researchers have developed three novel monoclonal antibodies that all have exceptional activity against human and mouse GATA2.   
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A UW-Madison researcher has developed a rabbit polyclonal antibody for methylated PKM2. There are three PKM2 arginine methylation sites R445, R447, R455. The antibody was generated using peptides enco...
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UW-Madison researchers have developed a CRISPR-based genome editing tool to study and modify PULs in B. uniformis. The B. uniformis PULs show distinct glycan-degrading functions and transcriptional co...
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A UW-Madison researcher has developed and characterized an anti-RBM20 polyclonal antibody rabbit preparation (which he calls the “RBM20 antibody”). The inventor expressed and purified the ...
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UW-Madison researchers disclose two mutant Bacteroides strains, BU ΔPUL18 and BU ΔPUL37, each with characteristics that could be useful in modulating the gut microbiome.
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UW-Madison researchers have developed a GFAP knockout mouse model, designated tm1Mes, that has been engineered to have an internal deletion of the Gfap gene that renders it completely non-functional. ...
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UW-Madison researchers have developed a mouse model of Alexander disease, designated B6.129S7 (Cg) Gfap tm2Mes, that was engineered as a knock-in of the R236H point mutation in the Gfap gene; this is ...
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UW-Madison researchers have developed a mouse model of Alexander disease, designated FVB.129S7 (Cg) Gfap tm2Mes, that was engineered as a knock-in of the R236H point mutation in the Gfap gene; this is...
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UW-Madison researchers have developed a transgenic mouse, designated Tg73.7, that carries full-length copies of a human genomic clone of wild-type GFAP, including all introns and exons.
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UW-Madison researchers have developed a mouse model of Alexander disease, designated FVB.129S7 (Cg) Gfap tm3Mes, that was engineered as a knock-in of the R76H point mutation in the Gfap gene. This is ...
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Overload of protein granules in cells induces many forms of diseases, and is especially found in neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis as well as ver...
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Lactic acid bacteria constitute a large group of Gram-positive bacteria (over 200 species described), of which Lactobacillus is the largest genus in the lactic acid bacteria group. Members of the Lact...
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Normal vibration of vocal folds (aka vocal cords) depends on the tissue's composition and viscoelasticity. When that composition is altered by scarring or damage, the vibratory functionality of the vo...
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Described herein is a method of preparing an unbiased library of phage variants,comprising (a) preparing a population of “acceptor phage”; (b) removing an endogenoustarget gene and inserting gene ...
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The HRV proteases (3C and 2A) and the 3D polymerase have very important functions in virus replication cycle and virus-host interactions and are very intensively investigated for their role in develop...
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The commercially available E. coli strain BL21 λDE3 is commonly used for inducibly overexpressing recombinant proteins. Many derivatives of BL21 cells have been developed and commercialized, wi...
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UW Madison researchers' present invention is a set of two, new transgenic mouse multiple myeloma (MM) cell lines. Transgenic mice were developed expressing mutations in RAS pathway genes found in ...
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UW-Madison researchers have cloned, sequenced and characterized the genome from an isolate of the RV-C45 genotype, and they’ve provided the cDNA for a high titer HRV-C (C45-2A-D41K), as well as ...
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UW-Madison researchers have developed two cell lines derived from RPE-1 cells (which were obtained from ATCC), an immortalized, non-transformed human epithelial cell line. “PLK4 WTflox/Delta&rdq...
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Fibronectin (FN) is a large glycoprotein that plays an important role in the formation of extracellular matrices that are necessary for embryogenesis, tissue renewal, and various pathophysiologic proc...
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Basal cell carcinoma (BCC) is the most common type of skin cancer, with around 3 million cases diagnosed each year. BCC involves the basal cells, which are in the deepest layer of the epidermis, the o...
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