Wisconsin Alumni Research Foundation

Technology

Broadly protective influenza B virus vaccines

UW-Madison researchers have developed a series of mutant influenza B viruses that incorporate mutations in the HA1 protein that cause the virus to react with sera generated via exposure to the opposit...
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Yoshihiro Kawaoka, Gabriele Neumann | P220144US02

Technology

MUTANT ACE2 PROTEINS AND METHODS OF USING SAME

UW-Madison researchers have identified novel ACE2 mutants having enhanced activity and/or specificity in hydrolyzing angiotensin II. ACE2 (angiotensin converting enzyme 2) is a key metalloprotease of ...
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Philip Romero, Peter Heinzelman | P210188WO01

Technology

RECOMBINANT MULTIVALENT INFLUENZA VIRUSES

The present invention relates to a novel bivalent coronavirus/influenza virus vaccine (called CoroFlu). The vaccine comprises a coronavirus antigen (a secreted version of the spike (S) protein of SARS...
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Yoshihiro Kawaoka, Gabriele Neumann | P200263US02

Technology

CARDIAC FIBROBLAST DERIVED EXTRACELLULAR MATRIX

UW-Madison researchers have discovered a novel marker in cardiac fibroblasts and myofibroblasts that reliably predicts extracellular matrix production in cultured cardiac fibroblasts. Sushi Domain Con...
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Eric Schmuck, Amish Raval, Sushmita Roy, Tianhua Zhou | P210363US02

WARF