Wisconsin Alumni Research Foundation

Technology

HUMAN BLOOD-BRAIN BARRIER TARGETING ANTIBODIES

UW-Madison researchers have identified new antibodies and related single-chain antibody fragments (scFvs) that bind and transport across the brain vasculature. These promising antibodies were discover...
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Eric Shusta, Charles Stutz, Loukas Goulatis, Julia Georgieva | P200063US02

Technology

RETINAL ORGANOID MODEL SYSTEMS

UW-Madison researchers have developed a retinal organoid model system for evaluating therapies that target genetic mutations. The inventors have discovered that genetic modifications that compromise t...
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David Gamm, Steven Mayerl | P210058US02

Technology

Kras Conditional Knockout Allele

Differentiation of normal stem cells into the correct cell lineage is a tightly controlled process that involves cell-cell and cell-extracellular matrix interactions as well as signaling through cellu...
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Jing Zhang | P210181US01

Technology

Microbial Glycans As A Target Of Human Intelectin

The present disclosure provides for methods of diagnosing and treating bacterial infections. Human Intelectin 1 (hIntL-1) has been shown to bind selectively to glycan components on bacteria including ...
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Laura Kiessling, Darryl Wesener, Kittikhun Wangkanont | P150027US02

Technology

Probiotic Function Of Human Intelectin

The present disclosure provides for methods providing a pre/probiotic agent to a subject. Human Intelectin 1 (hIntL-1) has been shown to bind selectively to glycan components on bacteria, thereby prom...
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Laura Kiessling, Darryl Wesener, Kittikhun Wangkanont, Federico Rey | P150027US04

WARF