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63 Results for 'Drug Delivery'
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Technology
Method Of In Vitro Differentiation Of Neural Stem Cells, Motor Neurons And Dopamine Neurons From Pri
Su-Chun Zhang, Xue-jun Li | P07445US
Technology
REAGENTS & METHODS FOR USING HUMAN EMBRYONIC STEM CELLS TO EVALUATE DEVELOPMENTAL TOXICITY FOR PHARMACEUTICAL COMPOUNDS & OTHER CHEMICALS
Gabriela Cezar | P06130US
Technology
Microbial Glycans As A Target Of Human Intelectin
Laura Kiessling, Darryl Wesener, Kittikhun Wangkanont | P150027US02
Technology
Potent Glycoprotein Antibody As A Therapeutic Against Ebola Virus
Yoshihiro Kawaoka, Peter Halfmann, Ayato Takada | P150303US02
Technology
Osmotic Enhancement Of Drug/Therapeutic Delivery To The Brain Following Infusion Or Injection Into The Cerebrospinal Fluid
Robert Thorne, Daniel Wolak, Michelle Pizzo | P160077US02
Technology
Probiotic Function Of Human Intelectin
Laura Kiessling, Darryl Wesener, Kittikhun Wangkanont, Federico Rey | P150027US04
Technology
Unimolecular Nanoparticles For Efficient Delivery Of Therapeutic Rna
Shaoqin Gong, Guojun Chen | P170119US02
Technology
Unimolecular Nanoparticles For Efficient Delivery Of Therapeutic Cationic Peptides
Shaoqin Gong, Wei Xu, Yuyuan Wang, Fabao Liu | P170128US02
Technology
Vector For Gene Silencing And Replacement And Methods Of Use Thereof
Erik Dent, Matthew Millette | P180170US02
Technology
Stable Theranostic And Therapeutic Nanoemulsions Using Triphilic Semifluorinated Amphiphiles
Sandro Mecozzi, Alexa Barres | P170292US02
Technology
Mineral Coated Microparticles For Gene Delivery In Chronic Wound Therapy
William Murphy, Andrew Khalil, Xiaohua Yu | P170173US02
Technology
Mineral Coated Microparticles For Co-Delivery Of Anti-Inflammatory Molecules With Nucleic Acids To Improve Gene Delivery Outcomes
William Murphy, Andrew Khalil, Xiaohua Yu | P170170US02
Technology
Human Pluripotent Stem Cell-Derived Brain Organoids For Cancer Modeling And Drug Screening
William Murphy, Elizabeth Aisenbrey, Elizabeth Torr, Victoria Harms, Gaurav Kaushik | P190185US02
Technology
An Ionic Liquid-Based Nanoemulsion Formulation For The Efficient Delivery Of Hydrophobic Therapeutic Agents
Sandro Mecozzi, Moira Esson | P180283US02
Technology
Methods And Culture Substrates For Controlled Induction Of Biomimetic Neural Tissues Comprising Singular Rosette Structures
Randolph Ashton, Gavin Knight | P170180US02
Technology
Polyplex Delivery System For Proteins, Nucleic Acids And Protein/Nucleic Acid Complexes
With an increasing interest in using the CRISPR/Cas9 system for gene editing, there comes a strong need to develop tools for delivering the CRISPR machinery safely and efficiently into cells. Existing...
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Shaoqin Gong, Yuyuan Wang, Krishanu Saha, Amr Abdeen | P180158US02
Technology
Nanocapsule Delivery System For Ribonucleoproteins
With the explosion of interest in using the CRISPR/Cas9 system for gene editing, there is a strong focus on developing tools for delivering the CRISPR machinery safely and efficiently into cells. Exis...
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Shaoqin Gong, Krishanu Saha, Guojun Chen, Amr Abdeen, Yuyuan Wang, Ruosen Xie | P170376US02
Technology
Engineered Probiotics as Systemic Therapeutic Delivery Platform
Polypeptides, such as enzymes, antibodies, hormones and cytokines, are useful therapeutic agents. However, routes for systemically introducing such polypeptides to a subject are limited. Oral administ...
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Jan Peter Van Pijkeren, Alan Attie, Mark Keller, Jeehwan Oh | P160109US02
Technology
S1mplex: A New Tool for Precision Gene Editing
New tools for human gene editing are rapidly advancing all sectors of biomedicine from basic biology to somatic gene therapy in the clinic. Precise editing of DNA sequences in the human genome can be ...
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Krishanu Saha, Jared Carlson-Stevermer, Amr Abdeen, Lucille Kohlenberg | P170309US02
Technology
An Injectable Nanovehicle for a Cancer Treatment Combination of Paclitaxel, Rapamycin and 17-AAG
Two-drug combinations of paclitaxel and rapamycin (an mTOR inhibitor) as well as paclitaxel and 17-AAG (an enhanced version of geldanamycin and Hsp90 inhibitor) have progressed into human clinical tri...
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Glen Kwon | P090383US03
Technology
Reagents for Bioreversible Protein Esterification
Chemoselective transformations are of key importance in modern chemical biology. Protein esterification can, for example, be employed for labeling, enhanced cellular uptake and other useful protein mo...
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Ronald Raines, Kalie Mix | P150262US03
Technology
Enhanced Drug Delivery Across the Blood-Brain Barrier: pH-Dependent Antibodies Targeting the Transferrin Receptor
Drug delivery to the brain is hampered by the presence of the blood-brain barrier (BBB), which excludes more than 98 percent of small molecule pharmaceuticals and nearly 100 percent of all protein and...
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Eric Shusta, Benjamin Tillotson | P150370US02
Technology
Phage-Cured Lactobacillus Strains for Therapeutic Delivery
In addition to key roles in food and biofuel production, probiotic strains of lactic acid bacteria are being exploited in medicine as therapeutic delivery vehicles. One obstacle is that bacteriophages...
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Jan Peter Van Pijkeren, Jeehwan Oh | P170020US01
Technology
Bioreversible Boronates Improve Drug Delivery
The utility of many biologic drugs is limited by inefficient delivery into cells. Strategies to overcome this limitation have included enhancing the attraction between positively charged drug agents a...
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Ronald Raines, Thomas Smith | P150009US02
Technology
Enhancing Cell Penetration to Improve Drug Delivery
The utility of many biologic drugs is limited by inefficient cellular delivery. There is a particular need for methods and reagents that facilitate delivery of peptides and proteins into the interior ...
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Ronald Raines, Kristen Andersen | P150031US02