Drug Discovery & Development
Photochemical Methods Of Making Cyclobutane Boronates And Related Compounds
Inventors: Tehshik Yoon, Spencer Scholz, Rowan Littlefield, Niecia Flikweert
The present technology relates generally cyclobutane boronates, including methods of preparation by exposing a mixture of a compound of Formula I in a solvent [Image Omitted] and a catalytic amount of a visible light sensitizer to provide a compound of Formula II, stereoisomers thereof, and/or salts of any of the foregoing. [Image Omitted] The cyclobutane boronate compounds are useful intermediates in the preparation of pharmaceutically active compounds as well as other useful compounds.
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