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60 Results for 'Cell lines'
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Technology
Cynomolgus Macaque Induced Pluripotent Stem Cell (iPSC) Line: Line CY1038
A UW-Madison researcher has developed an induced pluripotent stem cell (iPSC) line, called cy1038, from fibroblast cells from a male Cynomolgus Macaque that has a heterozygous MHC haplotype (M2/M4). T...
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John Maufort | P260416US01
Technology
Cynomolgus Macaque Induced Pluripotent Stem Cell (iPSC) Line: Line CY0682
A UW-Madison researcher has developed an induced pluripotent stem cell (iPSC) line, called cy0682, from fibroblast cells from a male Cynomolgus Macaque that’s homozygous for the M1 MHC haplotype. Th...
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John Maufort | P260415US01
Technology
Cynomolgus Macaque Induced Pluripotent Stem Cell (iPSC) Line: Line CY0928
A UW-Madison researcher has developed an induced pluripotent stem cell (iPSC) line, called cy0928, from fibroblast cells from a female Cynomolgus Macaque that’s homozygous for the M6 MHC haplotype. ...
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John Maufort | P260414US01
Technology
Cynomolgus Macaque Induced Pluripotent Stem Cell (iPSC) Line: Line CY0903
A UW-Madison researcher has developed an induced pluripotent stem cell (iPSC) line, called Cy0903, from fibroblast cells from a female Cynomolgus Macaque that’s homozygous for the M2 MHC haplotype. ...
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John Maufort | P260413US01
Technology
Adapted Rhinovirus C for Maximum Virus Yield
Human rhinoviruses (species A, B and C) encompass more than 160 types that are responsible for the majority of upper respiratory tract infections (common colds) and many of the lower respiratory tract...
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James Gern, Yury Bochkov, Ann Palmenberg, Kelly Watters | P160050US02
Technology
Probiotic Strain Collection to Study Prophages
UW-Madison researchers have developed a number of variants of lytic strain L. reuteri ∆Φ1attB1∆Φ2∆attB2 (WARF case P170020). They are:
L. reuteri∆Φ1, in which prophage #1 is deleted from th...
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Jan Peter Van Pijkeren, Jeehwan Oh | P230139US01
Technology
STAPHYLOCOCCUS SAPROPHYTICUS STRAIN COLLECTION
A UW-Madison researcher has compiled a large collection of Staphylococcus saprophyticus strains from various sources, and the present disclosure refers to a set of 100 clinical human samples from that...
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Caitlin Pepperell | P260153US01
Technology
FORWARD PROGRAMMED BLOOD-BRAIN BARRIER MODEL
UW-Madison researchers have developed a method for differentiation of human pluripotent stem cells (hPSCs) into endothelial cells (ECs) resulting in a model having improved fidelity to BBB gene expres...
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Eric Shusta, Sean Palecek, Sarah Boutom, Yunfeng Ding, Soniya Milind Tamhankar | P240333US02
Technology
GATA2 DEFICIENT CELL LINE AND METHODS OF SCREENING GATA2 VARIANTS
UW-Madison researchers have generated a new human GATA2 deficiency model. The model was generated using CRISPR-Cas9 targeting to deactivate one copy of the GATA2 gene in HUDEP-2 cells. This cell line,...
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Emery Bresnick, Kirby Johnson | P250085US02
Technology
CELL LINE: Lemo21-sufZM ("IMPROVED EXPRESSION STRAINS FOR FE-S CLUSTER PROTEINS")
UW-Madison researchers previously discovered that Escherichia coli BL21(DE3) and commercially available derivatives of it carry a deletion that results in an in-frame fusion of sufA and sufB genes wit...
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Patricia Kiley, Banerjee Rajdeep, Erin Mettert, Isabel Askenasy | P250352US02
Technology
CELL LINE: Lemo21-sufEC ("IMPROVED EXPRESSION STRAINS FOR FE-S CLUSTER PROTEINS")
UW-Madison researchers previously discovered that Escherichia coli BL21(DE3) and commercially available derivatives of it carry a deletion that results in an in-frame fusion of sufA and sufB genes wit...
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Patricia Kiley, Banerjee Rajdeep, Erin Mettert, Isabel Askenasy | P250352US01
Technology
CELL LINE: BL21(DE3)-sufEC ("IMPROVED EXPRESSION STRAINS FOR FE-S CLUSTER PROTEINS")
UW-Madison researchers previously discovered that Escherichia coli BL21(DE3) and commercially available derivatives of it carry a deletion that results in an in-frame fusion of sufA and sufB genes wit...
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Patricia Kiley, Banerjee Rajdeep, Erin Mettert, Isabel Askenasy | P250352US03
Technology
Keratinocyte Cell Line (From Little Brown Bat)
UW-Madison researchers have developed an immortalized keratinocyte cell line from the little brown bat (a species that is now endangered). They utilized that cell line to create a model of bat hiberna...
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Bruce Klein, Marcos Isidoro | P240382US01
Technology
Human Cell Line Natively Expressing A HaloTag Fusion To IST1, A Protein Involved In Membrane Trafficking And Endosomal Protein Sorting
A UW-Madison researcher has developed a novel cell line for studying the dynamics of the protein Ist1. They added a HaloTag onto the 3’ end of IST1 in a human RPE1 cell line. This cell lines provide...
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Anjon Audhya, Kevin Swift | P240165US01
Technology
A Single-Handed Petri Dish to Reduce Contamination Risk and Increase User Flexibility
UW-Madison researchers have developed a petri dish with locking mechanisms for single-handed operations. As cell culture workflows can be sensitive to contamination, single-handed operation allows use...
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Aleksandar Wood, Harpreet Singh | P190121US02
Technology
HOST FACTORS THAT ENHANCE VIRAL PRODUCTION VIA VIRALLY DRIVEN FITNESS-BASED CRISPR SCREENING
UW-Madison researchers have developed a new screening approach for identifying host factors that impact influenza viral production after the initial infection, and have used the screen to identify doz...
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Andrew Mehle, Cason King | P230021US02
Technology
NOVEL CELL LINES SUPPORTIVE OF ROBUST LACTATE DEHYDROGENASE VIRUS (LDV) INFECTION
A UW-Madison researcher has created a cell line capable of growing LDV virus in vitro. The inventor explains that he made an educated guess as to what the receptor for this virus might (CD163) be and ...
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Adam Bailey, Teressa Shaw, Cody Warren | P230385US01
Technology
NOVEL CELL LINES SUPPORTIVE OF ROBUST ARTERIVIRUS INFECTION
A UW-Madison researcher has developed FcRn-overexpressing cell lines that are susceptible to arterivirus infection. Through a genetic screen, the inventor discovered that the neonatal Fc receptor (FcR...
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Adam Bailey, Teressa Shaw, Cody Warren | P230384US01
Technology
VACO6
A UW-Madison researcher has established a cell line, called VACO6, from a discarded tissue specimen of a surgically resected primary human colon cancer. The detailed characteristics of the clinical do...
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James Willson | P230180US01
Technology
RHESUS MACAQUE INDUCED PLURIPOTENT STEM CELL (IPSC) LINE: LINE Rh2431
A UW-Madison researcher has developed a Rhesus Macaque induced pluripotent stem cell (iPSC) line, called the Rh2431 iPSC line.
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John Maufort | P230112US01
Technology
CYNOMOLGUS MACAQUE INDUCED PLURIPOTENT STEM CELL (IPSC) LINE: LINE cy0657
A UW-Madison researcher has developed a Cynomolgus Macaque induced pluripotent stem cell (iPSC) line, called the cy0657 iPSC line.
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John Maufort | P230113US01
Technology
METHOD FOR DIFFERENTIATION OF BRAIN MURAL CELLS FROM HUMAN PLURIPOTENT STEM CELLS
UW-Madison researchers disclose a new method for differentiating brain mural cells – encompassing pericytes and vascular smooth muscle cells – from hPSCs. The inventors used their previously discl...
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Eric Shusta, Benjamin Gastfriend, Sean Palecek | P220005US02
Technology
Immortalized Vocal Fold Fibroblasts
Normal vibration of vocal folds (aka vocal cords) depends on the tissue's composition and viscoelasticity. When that composition is altered by scarring or damage, the vibratory functionality of th...
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Susan Thibeault, Xia Chen | P190232US01
Technology
SufFeSient Cells
The commercially available E. coli strain BL21 λDE3 is commonly used for inducibly overexpressing recombinant proteins. Many derivatives of BL21 cells have been developed and commercialized, with pro...
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Patricia Kiley, Erin Mettert | P190138US01
Technology
Vq Myeloma Cell Lines
UW Madison researchers' present invention is a set of two, new transgenic mouse multiple myeloma (MM) cell lines. Transgenic mice were developed expressing mutations in RAS pathway genes found in ...
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Jing Zhang | P210035US01