Pluripotent Stem Cells
GENERATION OF HOXA-EXPRESSING HEMOGENIC ENDOTHELIUM WITH
ENHANCED T CELL POTENTIAL FROM HPSCS
WARF: P200133US02
Inventors: Igor Slukvin, Ho Sun Jung
The Invention
The present invention provides methods of creating a population of hemogenic endothelial cells with arterial specification and enhanced T cell potential. The methods involve inducing the expression of a SOX17 transgene in human pluripotent stem cells starting at day 2 of differentiation. Stem cells that express the SOX17 transgene are also provided.
Additional Information
For More Information About the Inventors
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