Reprogrammed Stem Cell Line for Research: IISH3i-CB6
Inventors: Igor Slukvin, Kejin Hu, James Thomson
The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a transgene-free iPSC line generated by reprogramming cord blood cells.
Reprogramming blood cells to induced pluripotent stem cells (iPSCs) provides a novel tool for studying blood development in vitro.
UW–Madison researchers have developed a reprogrammed iPSC line called IISH3i-CB6. Their method generates iPSCs free of transgene and vector sequences from human bone marrow and cord blood mononuclear cells using non-integrating episomal vectors.
- Reprogrammed iPSCs for research
- Research-grade stem cells
- Hu K., Yu J., Suknuntha K., et al. 2011. Efficient Generation of Transgene-Free Induced Pluripotent Stem Cells from Normal and Neoplastic Bone Marrow and Cord Blood Mononuclear Cells. Blood. 117, e109–e119.