Bone Morphogenetic Protein-1 Biological Materials
Inventors: Daniel Greenspan, Kazuhiko Takahara
The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing materials for expressing BMP-1.
Bone morphogenetic proteins (BMPs) are critical for the formation of cartilage and its conversion into bone.
UW-Madison researchers have developed DNA clones, antibodies, vectors and cell lines for expressing bone morphogenetic protein-1 (BMP-1). These materials can be used to produce recombinant BMP-1.
- Detecting BMP-1 protein and RNA
- Potentially useful in high throughput screening for inhibitors of BMP-1
- May be used in X-ray crystallography prior to drug design