Wisconsin Alumni Research Foundation

Therapeutics & Vaccines
Therapeutics Vaccines
Anti-Apoptotic Vector And Method Of Using The Same
WARF: P210046WO01

Inventors: Robert Nickells, Gillian McLellan, Ryan Donahue

The Invention
UW Madison researchers' present invention provides vectors for delivery of an anti-apoptotic therapy. The vectors include a phosphoglycerate kinase (Pgk) promoter operably connected to a polynucleotide encoding an anti-apoptotic BCL2 protein (e.g., BCLXL). The vectors may be 5 used in methods of treating conditions associated with apoptosis, including glaucoma.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Rafael Diaz at [javascript protected email address] or 608-960-9847