Wisconsin Alumni Research Foundation

Therapeutics & Vaccines
Therapeutics Vaccines
19,26,27-trinor-1alpha,25-dihydroxyvitamin D3 Compounds
WARF: P05370US

Inventors: Hector DeLuca, Lori Plum, Pawel Grzywacz, Margaret Clagett-Dame

The Invention
This invention relates to vitamin D compounds, and more particularly to 19,26,27-trinor-1α,25-dihydroxyvitamin D3 compounds such as 2α-methyl-19,26,27-trinor-(20S)-1α,25-dihydroxyvitamin D3 (“P10”), 2β-methyl-19,26,27-trinor-(20S)-1α,25-dihydroxyvitamin D3 (“T-74”), and 2-methylene-19,26,27-trinor-(20S)-1α, 25-dihydroxyvitamin D3 (“BM”), and to pharmaceutical formulations that include these compounds or mixtures thereof. The invention also relates to the use of P10, T-74, and BM, salts thereof, and mixtures thereof in the preparation of medicaments for use in treating various diseases.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Rafael Diaz at [javascript protected email address] or 608-960-9847