Wisconsin Alumni Research Foundation

Therapeutics & Vaccines
Therapeutics Vaccines
IDO Activity As A Marker Of Tumor Immune Escape And IDO Inhibitors As A Means Of Enhancing T Cells Response To Antigen Specific Vaccine
WARF: P190013US02

Inventors: Douglas McNeel, Christopher Zahm, Laura Johnson

The Invention
The present invention from UW Madison researchers provides compositions and methods of treating prostate cancer using a combination of a DNA vaccine, PD-1 inhibitor and an IDO inhibitor. Further, methods of measuring IDO activity as a way to identify a subpopulation of subjects with prostate cancer that may benefits from the treatment methods described herein are provided.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Andy DeTienne at [javascript protected email address] or 608-960-9857