Therapeutics & Vaccines
Influenza M2 Protein Mutant Viruses As Influenza Live Attenuated Vaccines
Inventors: Yoshihiro Kawaoka, Tokiko Watanabe
A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.
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