WARF TECHNOLOGIES

The inventors have discovered that certain alkylphosphocholine analogs are preferentially taken up by multiple myeloma tumor cells, as compared to non-tumor cells. The inventors have further demonstrated that preferential uptake of such compounds can be used in the therapeutic treatment of multiple myeloma, as well as in multiple myeloma detection/imaging applications. In therapeutic treatment, the alkylphosphocholine targeting backbone includes a radionuclide that locally delivers therapeutic dosages of radiation to the multiple myeloma tumors cells that preferentially take up the alkylphosphocholine analog. In detection/imaging applications, the alkylphosphocholine targeting backbone includes a detection moiety, such as a fluorophore or a radiolabel.

For More Information About the Inventors

• Jamey Weichert
• Mario Otto
• Fotios Asimakopoulos

Tech Fields

• Therapeutics & Vaccines : Oncology