Therapeutics & Vaccines
Compositions And Methods For The Inhibition Of Fibrosis
Inventors: Bianca Tomasini-Johansson, Glen Kwon, Pawel Zbyszynski, Nathan Sandbo, Ksenija Bernau
Described herein is a mono-end PEGyated functional upstream domain (FUD), pharmaceutical compositions, and its use to inhibit fibrosis such as organ fibrosis, idiopathic pulmonary fibrosis and fibrosis associated with cancer. Also included are methods of probing for injured or repairing tissue in an individual in need thereof using the mono-end PEGyated-FUD.