Wisconsin Alumni Research Foundation

Therapeutics & Vaccines
Therapeutics Vaccines
Circular Strained Zymogen Compositions And Methods Of Use
WARF: P190190US02

Inventors: Ronald Raines, Ian Windsor

The Invention
Disclosed herein are circular zymogens of RNase 1 that have a proteolytic cleavage site and are activated by a specific protease. These circular zymogens are useful for treatment of disorders that are characterized by a specific protease (e.g., HIV-1 protease).
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854