Wisconsin Alumni Research Foundation

Therapeutics & Vaccines
Therapeutics Vaccines
COVID-19 Vaccine
WARF: P200268US03

Inventors: Joseph Barbieri, Eric Johnson, Sabine Pellett, William Tepp, Amanda Przedpelski

The Invention
Provided herein are antigenic peptides comprising the SARS-CoV-2 spike protein receptor binding domain (CRBD) polypeptide or portions thereof, linked to a non-catalytic, non­toxic tetanus toxin variant (i.e., a modified tetanus toxin or "MTT") and vaccine compositions comprising the same. In addition, provided herein are methods for making and using CRBD­MTT fusion proteins as immunogenic agents.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Rafael Diaz at [javascript protected email address] or 608-960-9847