Therapeutics & Vaccines
METHOD FOR SELECTING ANTIGENIC VIRAL VACCINE AND THERAPEUTIC SEQUENCES
Inventors: David O'Connor, Thomas Friedrich, Marc Johnson
UW-Madison researchers, in collaboration with a professor from the University of Missouri, propose using the cryptic lineages (4-24 amino acid substitutions) of the SARS-CoV-2 spike protein sequence to better predict future variants. These variant sequences could then be used in the design of future vaccines to confer enhanced protection. Further, such sequences could be used in the production of antibodies for treating infected individuals.